Monosymptomatic bedwetting.

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TitoloMonosymptomatic bedwetting.
Tipo pubblicazioneJournal Article
Year of Publication1992
AutoriDjurhuus, JC, Nørgaard, JP, Rittig, S
JournalScand J Urol Nephrol Suppl
Volume141
Pagination7-17; discussion 18-9
Date Published1992
ISSN0300-8886
Parole chiaveArginine Vasopressin, Child, Circadian Rhythm, Deamino Arginine Vasopressin, Enuresis, Female, Humans, Male, Mental Disorders, Polyuria, Sleep Disorders, Urinary Bladder Diseases
Astratto

An update of the pathogenesis and treatment of monosymptomatic bedwetting is presented. This frequently occurring entity seems to have a multifactorial pathogenesis incorporating arousal disturbances and disturbances to the circadian rhythm of diuresis modulating hormones. It has recently been substantiated that the bladder reservoir function in monosymptomatic bedwetting is normal. This is further underlined by the fact that treatment of instability of the bladder has proven futile. In a substantial part of the monosymptomatic bedwetters the changes in circadian rhythm of antidiuretic hormone can be counteracted by desmopressin diacetate (DDAVP), which abolishes the symptom in more than 2/3 of the patients. Monitoring circadian rhythms of arginine vasopressin (AVP) and treatment with DDAVP have led to increased understanding of the pathogenesis of monosymptomatic bedwetting and opened new fields of investigation.

Alternate JournalScand J Urol Nephrol Suppl
Citation Key119
PubMed ID1609254

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